Cystic Fibrosis and CFTR Mutations Quiz

What is the primary cause of cystic fibrosis?

• A viral infection

• A faulty gene affecting CFTR protein production

• An autoimmune disorder

• A bacterial infection

How do class one mutations affect CFTR protein production?

• They lead to premature stopping of protein production

• They enhance the protein's function

• They cause the protein to be overproduced

• They have no effect on protein production

What is the role of a 'read through' drug in treating class one mutations?

• It overrides the stop signal to continue protein assembly

• It corrects the protein's structure

• It enhances the protein's function

• It stops the protein production

What is the function of a corrector drug like Orkambi in class two mutations?

• It increases the protein's production rate

• It corrects the protein's structure to pass quality control

• It enhances the protein's function

• It stops the protein production

How do potentiators help in class three and four mutations?

• They increase the protein's production rate

• They correct the protein's structure

• They enhance the protein's function by ensuring proper fuel flow

• They stop the protein production