Pharmacokinetics_Bioavailability

What does pharmacokinetics study?

• What a drug does to the body.

• The events that happen to a drug from administration to excretion.

• The chemical structure of drugs.

• The interaction between drugs and receptors.

Which of the following is NOT one of the four main processes involved in a drug's journey through the body?

• Absorption

• Distribution

• Synthesis

• Metabolism

Why are peptide drugs like insulin typically not given orally?

• They are too large to be absorbed.

• They are easily degraded by stomach acid and digestive enzymes.

• They are highly lipid-soluble and cannot cross cell membranes.

• They require active transport mechanisms not present in the digestive tract.

Are you enjoying the video lesson?

• Yes

• No

Where does a weak acid drug primarily get absorbed in the digestive tract?

• Small intestine

• Large intestine

• Stomach

• Esophagus

Compared to an intravenously administered drug, what is generally true about the bioavailability of an orally administered drug?

• It is always 100%.

• It is significantly lower.

• It is higher due to first-pass metabolism.

• It is unpredictable and cannot be measured.