IP3 and DAG

The video explores an alternative function of G proteins, focusing on the role of PIP2 in increasing intracellular calcium ion concentration. It explains the mechanism of enzyme activation by G proteins, highlighting the role of phospholipase C in producing IP3 and diacylglycerol. The video further discusses how IP3 facilitates calcium release from the endoplasmic reticulum, leading to cellular responses mediated by calmodulin and protein kinase. Additionally, it covers the activation of protein kinase C by diacylglycerol, emphasizing the importance of phosphorylation in cellular signaling.

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