Uroporphyrinogen III Synthase: Physiology, Biochemistry, and Organic Mechanism

The video explores the enzyme uroporphyrinogen 3 synthase, its role in converting hydroxymethyl bylane to uroporphyrinogen 3, and the genetic implications of its deficiency, leading to congenital erythropoietic porphyria. The enzyme's mechanism involves cyclization and D ring inversion. The video also discusses the biological significance of uroporphyrinogen 3 in heme synthesis and its applications, including the synthesis of heme B, heme A, and vitamin B12.

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