Aldehyde Dehydrogenase: Physiology. Biochemistry, and Mechanism

The video tutorial explores the metabolism of ethanol in the human body, focusing on the liver's role. It explains how ethanol is converted to acetaldehyde by alcohol dehydrogenase and further metabolized to acetic acid by aldehyde dehydrogenases. The tutorial details the enzyme mechanisms, including the role of NAD and water in the reaction, and highlights the structural aspects of the enzymes involved. It also clarifies the differences between alcohol and aldehyde dehydrogenases and discusses the toxic effects of acetaldehyde and acetic acid.

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