Isoleucine Deamination and Oxidation

The video tutorial explains the catabolic pathway of isoleucine, a branched-chain amino acid. It covers the initial reactions involving transaminase and the alpha-ketoacid dehydrogenase complex, leading to the production of NADH. The process of beta oxidation is discussed, highlighting the generation of FADH2 and reduced ubiquinol. The catabolism of Propionyl CoA is detailed, including its conversion to succinyl CoA via vitamin B12-dependent reactions. The video concludes with a calculation of the energy yield from isoleucine catabolism.

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