Malate-Aspartate Shuttle Mitochondrial NADH Transport

The video explains the challenge of transporting NADH from the cytosol to the mitochondria due to the lack of NADH transporters. It introduces the malate-aspartate shuttle as a solution, where electrons are transferred via malate. The process involves converting aspartate to oxaloacetate, then to malate, which carries electrons into the mitochondria. Inside, malate is converted back, regenerating NADH for the electron transport chain. The video concludes with a preview of the Glycerophosphate shuttle as an alternative method.

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