Jay Bradner: Open-source cancer research

The speaker discusses their journey from Chicago to Boston, focusing on cancer and chemistry. They highlight the inadequacy of current cancer treatments and the challenges posed by the undruggable genome. The talk introduces JQ1, a molecule developed to target the BRD4 protein in rare cancers. The speaker emphasizes the importance of open source and crowdsourcing in drug discovery, sharing JQ1 with various labs to accelerate research. The talk concludes with future plans for JQ1 and the role of academic centers in drug discovery.

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