In Search of a Mechanism

The video explores a mechanistic approach to understanding rare migraines, focusing on genetic mutations and their role in disease pathophysiology. It highlights the discovery of three genes linked to hemiplegic migraine, emphasizing their involvement in ion transport and electrical activity. The research challenges traditional views of migraines as vascular headaches, suggesting a neuronal basis. It also draws parallels between migraines and epilepsy, explaining why anti-seizure medications may be effective for migraines.

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