Adenosine Deaminase Deficiency (Part 1) How Does dATP Accumulate

Adenosine Deaminase Deficiency (Part 1) How Does dATP Accumulate

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Science, Chemistry

University

Hard

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The video explores purine metabolism, focusing on adenosine deaminase and its broad specificity. It discusses the consequences of adenosine deaminase deficiency, leading to deoxy ATP accumulation and inhibition of ribonucleotide reductase. This inhibition affects DNA synthesis and the immune response. The video explains equilibrium reactions and Le Chatelier's principle in the context of deoxy ATP production, highlighting the importance of understanding these biochemical processes.

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OPEN ENDED QUESTION

3 mins • 1 pt

What new insight or understanding did you gain from this video?

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