Myostatin | Negative Regulation of Skeletal Muscle Growth

The video discusses myostatin, a protein that regulates muscle growth by inhibiting it. It explains the signaling pathway involved in muscle protein synthesis, highlighting the roles of AKT, mTOR, and FOXO. Myostatin's inhibitory function is detailed, including its impact on muscle growth and potential therapeutic applications for muscle loss in the elderly. The video also covers genetic knockouts of myostatin, leading to excessive muscle growth, and the associated risks of inhibiting myostatin, particularly concerning heart and bone health.

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