Leucine Deamination and Oxidation

The video tutorial explains the catabolic pathway of leucine, highlighting its differences from valine catabolism. It details the enzymatic reactions involved, including the role of transaminase and dehydrogenase enzymes. The tutorial discusses the energy yield from leucine catabolism, emphasizing the formation of a proton gradient and the production of NADH. It also covers the biochemical pathways leading to the formation of acetyl CoA and acetoacetate, concluding with a summary and yield calculation of the entire process.

What is the significance of NADH and FADH2 in the energy yield from leucine catabolism?

Explain the biotin-dependent carboxylation process in the context of leucine metabolism.

Discuss the role of glucagon in the catabolism of amino acids, particularly leucine.

How does the catabolism of leucine contribute to the TCA cycle?