mTOR Signaling Pathway: mTOR Complexes, Regulation and Downstream effects

The video provides an in-depth look at mTOR signaling, focusing on the two complexes, mTORC1 and mTORC2, their regulatory mechanisms, and their functions within the cell. mTORC1 is involved in protein synthesis and autophagy inhibition, while mTORC2 regulates apoptosis and glucose metabolism. The video also discusses the discovery of mTOR and its role as a master regulator of cell growth and survival.

What are the effects of mTORC1 on protein synthesis and degradation?

Discuss the relationship between mTOR and autophagy.

Identify the inhibitors of mTORC1 and their mechanisms of action.

How does mTORC2 differ from mTORC1 in terms of function?