Eicosanoid Biosynthesis [Part 1] | Prostaglandins & Thromboxane A2

The video tutorial by Kevin Tolkoff explains the biosynthetic pathway of eicosanoids, focusing on the transformation of arachidonic acid into various compounds like prostaglandins and thromboxanes. It details the role of phospholipase A2 in releasing arachidonic acid from the plasma membrane and the subsequent synthesis of prostaglandins and thromboxanes. The video also discusses the functions of these compounds, particularly in inflammation and platelet activity, and introduces the upcoming topic of leukotriene synthesis.

How does the inflammatory stimulus affect the production of prostaglandins?

What triggers the activation of the eicosanoid pathway?

What is the role of endothelial cells in the eicosanoid pathway?