Allopurinol Mechanism of Action for Gout

The video discusses the mechanism of action of allopurinol, a drug used to manage gout by inhibiting xanthine oxidase, thereby reducing uric acid levels. It explains the purine degradation pathway, the role of xanthine oxidase, and how uric acid accumulation leads to gout and inflammation. The video also covers the pharmacological approach to reducing uric acid and the specific mechanism by which allopurinol functions, along with guidelines for its use in preventing gout attacks.

How does the accumulation of uric acid lead to gout?

What is the significance of inhibiting xanthine oxidase in the treatment of gout?

Why is allopurinol not used during an acute gout attack?