Passerini Reaction

The video tutorial explores the Passerini reaction, focusing on isonitriles, their formation, stability, and reactivity. It discusses the Passerini reaction mechanism, its applications in library synthesis, and ongoing research into enantioselective versions. The tutorial highlights the importance of isonitriles in chemistry, their unique properties, and their role in creating diverse chemical libraries.

What are isonitriles and how do they differ from isocyanates?

What role does pyridine play in the reaction involving isonitriles?

Explain the significance of the zwitterionic form of isonitriles.

What are the implications of the high delta G of activation for isonitriles?

Describe the mechanism of the Passerini reaction.

How does the Passerini reaction contribute to library synthesis in chemistry?

What advancements have been made in enantioselective versions of the Passerini reaction?