Human mini-livers successfully function in rats

Researchers at the University of Pittsburgh have developed functioning human mini livers using human skin cells, which were reverted to a stem cell state. These induced pluripotent stem cells were then differentiated into liver cells using chemicals and hormones. The lab-grown livers were transplanted into immunosuppressed mice to test their functionality.

What is the significance of using human skin cells in the development of mini livers?

• They are easily accessible

• They have a higher success rate

• They are less likely to be rejected

• They can be used for other organs

How long after the transplant were the mice dissected to examine the implanted organ?

• Two days

• Four days

• One week

• Three days