Proteasome Function

The video explains the structure and function of the 26S proteasome, likening it to a molecular garbage can. It describes how ubiquitinated proteins are targeted for degradation, with the proteasome opening its lid to allow entry. The process involves ATP hydrolysis, which facilitates protein unfolding and cleavage into smaller peptides. The proteasome's unique threonine protease activity is highlighted, emphasizing its role in recycling proteins for amino acid reuse.

Describe the structural features of the proteasome and how they relate to its function.

What is the primary function of the proteasome in cellular processes?

How does the structure of the proteasome imply its function as a 'molecular garbage can'?

Discuss the significance of polyubiquitination in the degradation of damaged proteins.

Explain the process of how a ubiquitinated protein is recognized and processed by the proteasome.

What role does ATP play in the functioning of the proteasome?

What are the end products of protein degradation by the proteasome?