Metronidazole | Bacterial Targets, Mechanism of Action, Adverse Effects

This video lesson covers the antibiotic metronidazole, also known as Flagyl. It discusses its properties, absorption, and distribution, highlighting its effectiveness against obligate anaerobes and some protozoa. The mechanism of action involves DNA damage through reactive oxygen species. The video also outlines infections treated by metronidazole, such as Clostridium difficile and brain abscesses, and details adverse reactions, including gastrointestinal and nervous system effects. A key warning is to avoid alcohol consumption during treatment due to disulfiram-like reactions.

What is metronidazole commonly known as?

What are the primary bacterial targets for metronidazole?

List some infections that metronidazole is used to treat.

Describe the mechanism of action of metronidazole.

How does metronidazole affect anaerobic bacteria specifically?

What are some common adverse reactions associated with metronidazole?

Explain the significance of avoiding ethanol consumption while taking metronidazole.