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The video covers three main topics: the COVID-19 situation in the US, highlighting the death toll and infection rates; the Georgia Senate runoff elections, which could determine the Senate majority; and the controversy surrounding the valuation of Prince's estate, with the IRS disputing the submitted figures.

What is the current death toll from COVID-19 in the US as mentioned in the text?

What are experts anticipating regarding COVID-19 cases and deaths after the holiday gatherings?

Who are the candidates in the Georgia Senate runoff elections?

What is the significance of the upcoming Georgia Senate elections for the Republican party?

What controversy is mentioned regarding Prince's estate?