Use Order of operation to simplify the expression

The video tutorial explains the order of operations, focusing on parentheses, multiplication, and division. It demonstrates simplifying expressions with negative numbers and multiplying fractions by whole numbers. The tutorial concludes with a final calculation, resulting in the answer of 13.

What is the first step to take when solving an expression with parentheses?

How should multiplication and division be approached in an expression?

What happens when you add a negative number to another negative number?

How do you multiply a fraction by a whole number?

What is the final answer when simplifying the expression involving -1/4 and -52?