Hereditary Spherocytosis | Pathophysiology, Symptoms, Diagnosis and Treatment

The video provides a comprehensive overview of hereditary spherocytosis, a common hemolytic anemia caused by defects in red blood cell membrane proteins. It covers the genetic basis, pathophysiology, signs and symptoms, diagnostic methods, and treatment options. The condition is more prevalent in northern European populations and can range from mild to severe. Diagnosis involves identifying signs of hemolysis and specific tests, while treatment includes folic acid supplementation, blood transfusions, and potentially splenectomy.

How does the size of spherocytes compare to normal red blood cells?

Discuss the role of reticulocytes in hereditary spherocytosis.

What complications can arise from hereditary spherocytosis?

What treatment options are available for patients with hereditary spherocytosis?