Grignard Reaction

The video explains Grignard reactions, a method to form carbon-carbon bonds, developed in 1912. It details the reaction mechanism, where magnesium inserts into a carbon-halogen bond, creating a nucleophilic carbon. This allows Grignard reagents to react with carbonyl compounds, forming alcohols. The reaction must occur in anhydrous conditions to prevent destruction of the Grignard reagent. Examples include reactions with aldehydes, ketones, and esters, highlighting the versatility and importance of Grignard reactions in organic synthesis.

How does a Grignard reagent react with carbonyl-containing compounds?

What happens when a Grignard reagent comes into contact with water?

Discuss the outcome of a Grignard reaction with an ester compared to an aldehyde.