Complement 1 Classical Pathway

The video tutorial explains the complement system, a crucial part of the immune system, focusing on the classical pathway. It details the structure and function of antibodies, the activation of the complement system through antibodies, and the formation of C3 and C5 convertases. The tutorial also covers the role of C4 and C2 in the process and the formation of the membrane attack complex, which ultimately lyses pathogens.

What is the complement system and its role in the immune response?

Describe the three pathways of complement system activation.

What happens when an antibody complexes with an antigen?

Explain the role of C1 in the complement activation process.

What is the significance of the thioester bond in C4?

How does C3 convertase function in the complement system?

What protective mechanisms prevent complement proteins from damaging host cells?

What are the consequences of C5 activation in the complement pathway?

How do the components C3A and C5A contribute to inflammation?

Discuss the role of the membrane attack complex in the immune response.