Clonal Selection EXPLAINED

The video tutorial explains the process of clonal selection, which ensures lymphocytes do not attack normal cells, preventing autoimmune conditions. It distinguishes between antigens and immunogens, highlighting that not all antigens trigger immune responses. The tutorial describes how the immune system recognizes self antigens to maintain tolerance and avoid attacking healthy cells. It also covers the immune response to foreign and abnormal antigens, leading to cell apoptosis. The stages of clonal selection, including positive and negative selection, are detailed, explaining how lymphocytes are tested for their ability to bind foreign antigens while avoiding self antigens.

What is clonal selection and why is it important for lymphocytes?

Define an antigen and explain its role in the immune response.

What distinguishes an immunogen from a regular antigen?

Explain the concept of tolerance in the immune system.

Describe the process of positive selection in lymphocyte development.

What happens to lymphocytes that fail to bind to foreign antigens during positive selection?

What is negative selection and why is it crucial for preventing autoimmune reactions?