Pharmacology of the Renin-Angiotensin-Aldosterone [RAAS] Pathway

The video tutorial explains the RAAS pathway, a negative feedback loop involving renin, angiotensin, and aldosterone, which regulates blood pressure and volume. It details the functions of angiotensin II, including vasoconstriction and aldosterone release. The video also covers pharmacological treatments targeting the RAAS system, such as ACE inhibitors, angiotensin receptor blockers, and aldosterone antagonists, explaining their mechanisms and effects on blood pressure and volume.

What is the mechanism of action of angiotensin receptor blockers (ARBs)?

Explain the effects of aldosterone on the kidneys.

What are the potential side effects of aldosterone receptor blockers?