Research Studies Could Be More Pragmatic, and More Useful

The video discusses the limitations of traditional research methods and introduces pragmatic trials as a solution to test treatments in real-world settings. It explains the difference between efficacy and effectiveness, using a chronic pain study as an example. The study compared opioid and non-opioid treatments, showing non-opioids can be as effective without addiction risks. Other pragmatic trials are highlighted, demonstrating their value in real-world applications. Challenges such as funding and complexity are acknowledged, emphasizing the need for more pragmatic trials to improve healthcare.

What were the findings of the comparative effectiveness trial regarding opioid and non-opioid medications?

Why might patients prefer non-opioid analgesics over opioids based on the study's results?

What challenges do pragmatic trials face in terms of funding and design?