What is Leptospirosis? How does it cause Organ Failure? & How to treat?

The video narrates the story of Silva, a farmer from Sri Lanka, who developed severe leptospirosis after refusing prophylactic treatment. The bacteria, Leptospira interrogans, entered his body through a wound, leading to severe symptoms like jaundice and pulmonary hemorrhages. Despite the high mortality risk, Silva was successfully treated with antibiotics, steroids, and plasma exchange, ultimately recovering from the life-threatening condition.

What is the primary way leptospira bacteria enter the human body?

• Through consumption of contaminated food

• Through direct contact with infected animals

• Through abrasions on the skin

• Through inhalation of contaminated air

Which symptom is characteristic of leptospirosis and was observed in Silva?

• Rash on the arms

• Conjunctival suffusion

• Swollen lymph nodes

• Severe headache

What was the reported mortality rate for pulmonary hemorrhages in leptospirosis?

• 10 to 20%

• 30 to 40%

• 50 to 70%

• 80 to 90%

What treatment was used to remove antibodies from Silva's circulation?

• Plasma exchange

• Blood transfusion

• Antibiotic therapy

• Hemodialysis

Which antibiotic was administered to Silva to target the leptospira bacteria?

• Ceftriaxone

• Azithromycin

• Doxycycline

• Amoxicillin