TED-ED: How aspirin was discovered - Krishna Sudhir

The video explores the history and development of aspirin, from its origins in willow bark used by ancient civilizations to its modern applications. Initially discovered by the Sumerians, the active ingredient salicin was later identified and synthesized, leading to the creation of aspirin by Bayer. Aspirin's medical uses expanded over time, addressing pain, inflammation, and heart disease, despite unknown mechanisms until the 20th century. Recent research highlights its potential in cancer prevention, though risks like bleeding and Reye's Syndrome exist. Aspirin remains a significant pharmaceutical, with ongoing research into its applications.

Which ancient civilization is credited with discovering the precursor to aspirin?

• The Sumerians

• The Romans

• The Chinese

• The Mayans

Who was the first to recommend the use of willow bark for pain relief?

• Hippocrates

• Johann Buchner

• Edward Stone

• Bayer

What compound did Johann Buchner identify and purify from willow bark?

• Salicin

• Prostaglandin

• Thromboxane

• Acetylsalicylic acid

What was the original brand name given to acetylsalicylic acid by Bayer?

• Paracetamol

• Ibuprofen

• Salicin

• Aspirin

What did scientists discover about aspirin's mechanism in the 1960s and 70s?

• It causes muscle growth

• It increases blood pressure

• It interrupts prostaglandin production

• It enhances digestion

What serious condition can aspirin overconsumption trigger in children?

• Reye's Syndrome

• Epilepsy

• Diabetes

• Asthma

How does aspirin help reduce the risk of heart attacks?

• By increasing blood sugar levels

• By reducing platelet clumping

• By lowering cholesterol

• By enhancing muscle strength