Devil in Details on Astra-Oxford Vaccine: SVB Analyst Porges

What was the main critique regarding AstraZeneca's vaccine trial results?

• The trial was too short.

• The efficacy was reported from a small subset of data.

• The vaccine was not effective at all.

• The trial did not include enough participants.

What unusual event occurred during the AstraZeneca vaccine trial?

• A switch to a different vaccine type.

• A complete halt of the trial.

• An increase in the number of participants.

• A change in the dosing schedule.

What is a key difference between AstraZeneca's vaccine and others?

• It requires only one dose.

• It uses a modified monkey adenoviral vector.

• It is administered orally.

• It uses a different type of spike protein.

What is the main concern when comparing different vaccine platforms?

• The color of the vaccine.

• The level of immunization achieved.

• The method of administration.

• The cost of production.

Why is it important to track adverse events in vaccine trials?

• To reduce the number of participants.

• To increase the trial's duration.

• To identify potential safety issues.

• To ensure the vaccine is effective.

What is the potential risk of a one in 10,000 adverse event when vaccinating a large population?

• It could lead to a minor inconvenience.

• It would have no impact.

• It could result in a significant number of adverse events.

• It would only affect a few individuals.

What is the significance of a 95% efficacy rate in vaccines?

• It suggests the vaccine is not safe.

• It means the vaccine is only partially effective.

• It indicates the vaccine is ineffective.

• It is considered very high and desirable.