Cytokines and Chemokines

The video tutorial explains the roles of cytokines and chemokines in immune cell communication. It covers cytokine nomenclature, major families, and their functions in TH1, TH2, TH17, and regulatory T cell responses. Chemokines are introduced, highlighting their role in cell migration and lymphoid tissue organization. The tutorial emphasizes understanding cytokine and chemokine names and functions to grasp immune responses better.

What is the primary function of cytokines in the immune system?

• To transport nutrients

• To provide energy to immune cells

• To communicate between immune cells

• To destroy pathogens directly

Which family of cytokines is known for communication between leukocytes?

• Interleukins

• Colony stimulating factors

• Tumor necrosis factors

• Interferons

What type of immune response is driven by TH1 cytokines?

• Regulation of immune response

• Humoral response

• Cellular immunity against intracellular pathogens

• Response to parasitic worms

Which cytokine is critical for T cell survival and proliferation in a TH1 response?

• IL-2

• IL-4

• IL-17

• IL-10

What is the main characteristic of a TH2 immune response?

• Activation of CD8 T cells

• Suppression of immune response

• Dominance of antibodies produced by B cells

• Recruitment of neutrophils

Which cytokine is responsible for promoting the growth of mast cells in a TH2 response?

• IL-5

• IL-10

• IL-17

• IL-4

What is a potential negative health consequence of an overly active TH17 response?

• Cancer

• Autoimmunity

• Irritable bowel syndrome

• Asthma

Which cytokine helps recruit neutrophils in a TH17 response?

• IL-4

• IL-22

• IL-8

• IL-10

What is the role of regulatory T cells in the immune system?

• To produce antibodies

• To activate B cells

• To suppress excessive immune response

• To enhance immune response

What does the 'L' in CCL2 stand for in chemokine nomenclature?

• Lipid

• Lymphocyte

• Leukocyte

• Ligand