Glutamate Semialdehyde Catabolism to Oxoglutarate

The video explores the catabolism of glutamate gamma semi aldehyde, highlighting its conversion to glutamate through aldehyde dehydrogenase. It also discusses the role of glutamate dehydrogenase, which exists in three types, each reacting differently with NAD and NADP. The video explains how energy charge affects amino acid catabolism, emphasizing the conversion of various amino acids to alpha ketoglutarate under low energy conditions.

Which molecules are converted to glutamate in the discussed pathways?

• Arginine and histidine

• Glutamine and glutamate gamma semi aldehyde

• Proline and lysine

• Histidine and lysine

What is the role of aldehyde dehydrogenase in the conversion process?

• It converts proline directly to glutamate

• It oxidizes glutamate gamma semi aldehyde to glutamate

• It catalyzes the formation of histidine

• It reduces glutamate to glutamine

How many types of glutamate dehydrogenase are there?

• One

• Two

• Three

• Four

Which molecule can react with all three types of glutamate dehydrogenase?

• Neither NAD+ nor NADP+

• NADP+

• NAD+

• Both NAD+ and NADP+

Under what conditions does amino acid catabolism primarily occur?

• High protein diet and high energy charge

• Low blood sugar and low energy charge

• High blood sugar and high energy charge

• Low protein diet and high blood sugar