BASICS of Fatty Acid Metabolism [Part 2] - Beta-oxidation of Fatty Acids

The video tutorial explains the beta oxidation pathway, detailing how fatty acids are metabolized into acetyl CoA units. It covers the liberation of fatty acids, their transport, and the enzymatic steps involved in beta oxidation. The process is illustrated with a 6-carbon example, showing how acetyl CoA is produced and enters the Krebs cycle, linking fatty acid metabolism to energy production.

What is the primary function of the beta oxidation pathway?

• To synthesize fatty acids

• To break down fatty acids for energy

• To convert glucose into glycogen

• To produce amino acids

How are fatty acids transported in the blood?

• Bound to serum albumin

• As triglycerides

• As free fatty acids

• Bound to hemoglobin

What is the role of the enzyme fatty acyl-CoA synthetase?

• To break down fatty acids

• To convert fatty acids into acyl-CoA

• To synthesize fatty acids

• To transport acyl-CoA into the mitochondria

What is the purpose of the carnitine shuttle?

• To move acyl-CoA into the mitochondrial matrix

• To transport glucose into the cell

• To convert fatty acids into glucose

• To synthesize ATP

Which enzyme is responsible for the initial oxidation step in beta oxidation?

• Acyl-CoA dehydrogenase

• Thiolase

• Enoyl-CoA hydratase

• Beta-hydroxyacyl-CoA dehydrogenase

What is produced at the end of each round of beta oxidation?

• Glucose

• Amino acids

• Acetyl-CoA

• Glycogen

How many carbons are removed from acyl-CoA in each round of beta oxidation?

• One

• Two

• Four

• Three

What happens to acetyl-CoA produced from beta oxidation?

• It is stored as fat

• It enters the Krebs cycle

• It is converted into glucose

• It is excreted as waste

Which of the following is a product of the Krebs cycle per acetyl-CoA?

• Two FADH2

• Three NADH

• One NADH

• Two ATP

What is the significance of the integration of beta oxidation with the Krebs cycle?

• It provides a direct source of glucose

• It allows for the synthesis of fatty acids

• It enhances energy production through ATP synthesis

• It reduces the need for oxygen