PS/NE 333 Exam 1 Review

Drug A has a lower therapeutic index (TI) compared to Drug B. Which drug is safer?

• Drug A is safer

• Drug B is safer

• Both drugs are equally safe.
• There is no way to know; TI does not assess drug safety

Which of the following does NOT pass through the cell membrane easily?

• Lipophilic molecules

• Hydrophobic molecules

• Charged molecules

• Small polar molecules

The extent to which a drug becomes completely available to its intended biological destination(s) is called:

The following is the list of methods of injections.

Which is the correct order of rate of absorption, from fastest to slowest?

• Intraperitoneal ->

  Intravenous ->

  Intramuscular ->

  Subcutaneous

• Intravenous ->

  Intramuscular ->

  Intraperitoneal ->

  Subcutaneous

• Subcutaneou ->

  Intramuscular ->

  Intraperitoneal ->

  Intravenous

• Intravenous ->

  Intraperitoneal ->

  Intramuscular ->

  Subcutaneous

Where in the body does the first pass metabolism take place?

• Lungs

• Liver

• Brain

• Mouth

Psychoactive drugs can pass through the Blood Brain Barrier

• True

• False

The ____ is an index of how long the process from absorption to elimination takes

In the neuron, information flows from axon terminal to the cell body

• True

• False

Which of the following improves the speed and conduction of the action potential in a neuron?

• Node of Ranvier

• Myelin Sheath

• Synaptic Vesicles

• Potassium Ions

Choose ALL the correct answers:

What happens to the neurotransmitters that are left in the synaptic cleft?

• Neurotransmitters stay in the synaptic cleft

• Recycled by presynaptic transporters

• Degraded by enzymes

• Transported out of the brain by presynaptic transporters