ConcorT VA Quiz

In India, ___% of naïve hypertensives present with high sympathetic overactivity (SO).

• 25%

• 45%

• 62%

• 73%

Approximately ___% of Indian hypertensives have high renin levels.

• 25%

• 35%

• 45%

• 62%

Sympathetic overactivity in younger hypertensives paves the way for:

• Renal failure

• Cardiometabolic diseases

• Malignancies

• GI disorders

Which cluster of diseases commonly share sympathetic overactivity as a mechanism?

• Diabetes, central obesity, CVD

• COPD, asthma, GERD

• Arthritis, thyroid, depression

• TB, malaria, dengue

Which is the major underlying cause of hypertension in India?

• High salt intake only

• Overactivated SNS & RAAS

• Endothelial dysfunction

• Smoking

Bisoprolol acts on which receptors in the kidney to prevent renin upregulation?

• Alpha-1 receptors

• Beta-2 receptors

• Beta-1 receptors in JG cells

• AT1 receptors

Telmisartan controls RAAS by blocking:

• AT2 receptors

• AT1 receptors

• Beta-1 receptors

• Calcium channels

Dual blockade of SNS & RAAS helps in:

• Faster atherosclerosis progression

• Breaking positive feedback loop

• Increased sympathetic activity

• Higher renin levels

As per ESC/ESH 2024 guidelines, initiation of ___ is recommended for most hypertensive patients.

• Monotherapy with BB

• Monotherapy with ARB

• Two drug combination therapy

• Triple therapy upfront

Which combination is well tolerated in patients with or without angina, as per ESC 2024 guidelines?

• ACEI + CCB

• ARB + BB

• BB + Diuretic

• ARB + CCB