Limit Test in Pharmaceutical Analysis

The limit test in pharmaceutical analysis is primarily used to:

• Identify impurities qualitatively

• Quantify the main drug content

• Detect the presence of inorganic impurities within permissible limits

• Test solubility of drug

Which reagent is commonly used in the limit test for chloride?

• Barium sulfate

• Silver nitrate

• Ammonium thioglycolate

• Lead acetate

The principle of limit test is based on:

• Formation of colored complex

• Comparison of turbidity or color with a standard

• Complete precipitation of impurity

• Measuring solubility

In the limit test for sulfate, the reagent used to precipitate sulfate ions is:

• Silver nitrate

• Lead acetate

• Barium chloride

• Ammonium hydroxide

The limit test for iron is carried out by reaction with:

• Thioglycolic acid

• Potassium thiocyanate

• Ammonium molybdate

• Barium chloride