Pharmacogenomics

What is pharmacogenomics?

• The study of how genes affect drug reponse

• The study of how drugs affect genes

• The study of the genetic makeup of drugs

• The study of drug metabolism

Which of the following factors can influence drug response?

• Genetics

• Environment

• Lifestyle

• All of the above

Pharmacogenomic testing can help to:

• Predict drug response

• Identify potential adverse drug reactions

• Optimize drug therapy

• All of the above

Pharmacogenomic testing is most useful for drugs that have a:

• Narrow therapeutic index

• Wide therapeutic index

• Low toxicity profile

• High efficacy

What is a polymorphism?

• A variation in the DNA sequence that occurs in at least 1% of the population

• A rare genetic mutation

• A genetic defect

• A change in gene expression