Liver disease

What is the most likely underlying cause of this patient's cirrhosis?

• Metabolic dysfuction associated with steatotic liver disease (MASLD)

• Hepatitis B infection

• Chronic alcohol use

• Autoimmune hepatitis

Which of the following best explains the pathophysiology of ascites in cirrhosis?

• Portal hypertension and hypoalbuminemia leading to fluid transudation

• Direct liver cell apoptosis causing fluid leakage

• Lymphatic obstruction by fibrotic tissue

• Excess bile production irritating the peritoneum

Which of the following findings indicates that this patient has decompensated cirrhosis? (More than 1 correct answer)

• Mildly elevated ALT

• Variceal bleeding

• Splenomegaly

• Ascites

Which of the following scoring systems is most appropriate for assessing the severity and prognosis of this patient’s liver disease?

• Glasgow Coma Scale (GCS)

• APACHE II score

• MELD score

• Wells score

What is asterixis?

Which of the following is a classic cutaneous sign of cirrhosis?

• A. Café-au-lait spots

• B. Spider angiomas

• C. Erythema nodosum

• D. Janeway lesions