Cervical intraepithelial Neoplasia

Cervical intraepithelial neoplasia (CIN) refers to:

• Malignant invasion of cervical tissue

• Premalignant changes in cervical epithelium

• Benign cervical growths

• Chronic cervicitis

CIN is most commonly caused by which of the following?

• Epstein-Barr virus

• Cytomegalovirus

• Herpes Simplex Virus

• Human Papillomavirus (HPV)

Which HPV types are considered high-risk for cervical cancer?

• 6 and 11

• 16 and 18

• 1 and 2

• 31 and 41

CIN I is confined to:

• Lower one-third of the epithelium

• Lower two-thirds of the epithelium

• Full thickness of the epithelium

• Stromal tissue

CIN III includes all of the following except:

• Carcinoma in situ

• Severe dysplasia

• Moderate dysplasia

• Full thickness epithelial involvemen

The gold standard for diagnosis of CIN is:

• Pap smear

• Colposcopy

• Cervical biopsy

• HPV DNA testing

The most appropriate management for a young woman with CIN I is usually

• Hysterectomy

• Immediate cone biopsy

• Observation with repeat cytology

• Chemotherapy

The most common site of CIN development is:

• Endocervix

• Posterior fornix

• Transformation zone

• External os

Atypical squamous cells of undetermined significance (ASC-US) on Pap smear should be followed up with

• Hysterectomy

• Repeat Pap smear or HPV testing

• No further testing

• Immediate LEEP

Treatment modality for persistent CIN II/III includes all of the following except

• Cryotherapy

• Loop electrosurgical excision procedure (LEEP

• Hysterectomy in select cases

• Oral antibiotics