Immune System Quiz

Which of the following immune cells is primarily responsible for the direct killing of virus-infected cells by recognizing viral peptides presented on MHC Class I molecules?

• B lymphocyte

• Natural Killer (NK) cell

• Helper T cell (CD4+)

• Cytotoxic T lymphocyte (CD8+)

All immune cells originate from which type of stem cell in the bone marrow?

• Myeloid Stem Cell

• Lymphoid Stem Cell

• Hematopoietic Stem Cell

• Mesenchymal Stem Cell

Which surface marker is characteristic of Helper T cells?

• CD8

• CD19

• CD4

• CD16

What is the primary function of Interferons (Type I IFNs) in the host immune response to viral infection?

• Directly neutralize free virus particles.

• Destroy infected cells lacking MHC I.

• Act as a warning signal to neighboring cells to produce antiviral proteins.

• Facilitate antibody-dependent cell-mediated cytotoxicity (ADCC).

Which type of viral infection is characterized by continuous viral replication that may cause long-term damage?

• Acute infection

• Latent infection

• Chronic infection

• Slow infection

Which immune cell is considered the most potent professional Antigen-Presenting Cell (APC) for activating naive T cells?

• Macrophage

• B cell

• Dendritic cell

• Neutrophil

The immune pathological effect where non-neutralizing antibodies facilitate viral entry into Fc receptor-bearing cells, leading to enhanced viral replication, is known as:

• Molecular Mimicry

• Cytokine Storm

• Antibody-Dependent Enhancement (ADE)

• Delayed-Type Hypersensitivity

Which of the following is NOT a viral strategy to evade the immune system?

• Hiding and latency

• Disrupting antigen presentation

• Enhancing host MHC Class I expression

• Subverting complement system

What is the typical timeframe for the onset of adaptive immune responses to viral infections?

• Immediate to hours

• Days to weeks

• Months to years

• Life-long latency

What is the major consequence of HIV infection in terms of immunodeficiency?

• Defect in phagocyte respiratory burst.

• Absence of mature B cells.

• Progressive depletion of CD4+ T helper cells.

• Impaired neutrophil extravasation.