Pain & Inflammation Part 1.2

Pain & Inflammation Part 1.2

University

23 Qs

quiz-placeholder

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Pain & Inflammation Part 1.2

Pain & Inflammation Part 1.2

Assessment

Quiz

Health Sciences

University

Hard

Created by

Benj Almero

FREE Resource

23 questions

Show all answers

1.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Which statement accurately describes the absorption, distribution, metabolism, and excretion of aspirin?

It is poorly absorbed from the stomach and excreted primarily by the liver.

It is absorbed from the large intestine, minimally bound to plasma proteins, and excreted in feces.

It is well absorbed from the stomach and upper small intestine, widely distributed, 50-80% bound to plasma proteins, metabolized in the liver, and excreted by the kidneys (with excretion increased by urine alkalinization).

It is primarily absorbed through topical application and metabolized in the muscles.

2.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What is the specific mechanism of action of aspirin?

It reversibly inhibits cyclooxygenase (COX) enzyme.

It selectively inhibits COX-2.

It primarily blocks phospholipase A2 (PLA2).

It irreversibly inhibits cyclooxygenase (COX) enzyme and thromboxane A2 (TXA2).

3.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What dose range of aspirin is used for its anti-platelet/anticoagulant effect for cardiovascular problems?

300-600 mg every 6-8 hours.

150-300 mg for periodic use.

In grams for anti-inflammatory effects.

Low doses (75-150 mg).

4.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What dose range of aspirin provides pain relief and fever reduction by inhibiting prostaglandin synthesis and resetting the hypothalamic thermostat?

300-600 mg every 6-8 hours, or 50-100 mg for periodic use.

Low doses (75-150 mg).

High doses (in grams).

Any dose, as its primary effect is anti-inflammatory.

5.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What dose of aspirin is typically needed for its anti-inflammatory effects in conditions like osteoarthritis (OA), rheumatoid arthritis (RA), and rheumatic fever?

Low doses (75-150 mg).

300-600 mg every 6-8 hours.

Higher doses (in grams, specifically 150-300 mg for periodic use).

It has no significant anti-inflammatory effect.

6.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Besides inhibiting prostaglandin synthesis, what other anti-inflammatory actions does aspirin have?

It destabilizes lysosomes and promotes migration of inflammatory cells.

It primarily blocks COX-2 selectively.

It stabilizes lysosomes and inhibits migration of inflammatory cells.

It increases the production of superoxide radicals.

7.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Which of the following are listed as common adverse effects of aspirin?

Agranulocytosis and aplastic anemia.

Renal tubular necrosis and hepatic encephalopathy.

Headache, tinnitus, dizziness, blurred vision, irritability, hyperventilation, and abdominal pain (gastrointestinal irritation).

Premature closure of the patent ductus arteriosus (PDA).

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