Chem-Computational Toxicity Tools Quiz

What does the BOILED-Egg model predict?

• Solubility

• Toxicity

• GI absorption and BBB permeation

• Metabolism

Which input format is most commonly used in toxicity prediction tools?

• CAS Number

• IUPAC Name

• SMILES

• InChI

Which tool gives toxicity classification based on LD50 values?

• SwissADME

• PROTOX II

• Pred-hERG

• CarcinoPred-EL

Which of the following tools predicts carcinogenicity using ensemble models?

• SwissADME

• CarcinoPred-EL

• LAZAR

• PreADMET

SwissADME predicts the following EXCEPT:

• Water solubility

• GI absorption

• Mutagenicity

• Lipophilicity

PROTOX II predicts which of the following?

• Protein-ligand docking

• hERG inhibition

• LD50 and toxicity class

• Carcinogenicity only

Which of the following is not needed in SwissADME analysis?

• SMILES

• InChI

• PubChem ID

• Drug Name

What is the full form of QSAR?

• Quantitative Structural Analysis Regression

• Quantitative Structure-Activity Relationship

• Quantum Structure Atomic Ratio

• Quality Statistical Active Regression

Which is the correct SwissADME output for bioavailability?

• Toxicity class

• Bioavailability Radar

• Protein binding

• QT interval

What is LD50?

• Dose lethal to 50% of the population

• Half the safe dosage

• Lowest effective dose

• Absorption rate