Quiz on Qualitative & Quantitative Disorders of Platelets

What is the size of petechiae?

• >1cm

• 1cm

• >3mm

• <2mm

Which condition is characterized by a decrease in platelet production due to bone marrow suppression?

• Thrombocytosis

• Immune thrombocytopenic purpura

• Aplastic anemia

• Von Willebrand disease

What is the primary cause of thrombocytopenia in extensive blood transfusions?

• Non-immune destruction

• Immune destruction

• Dilutional loss

• Increased platelet production

Which of the following is a qualitative platelet disorder?

• Thrombocytopenia

• Aplastic anemia

• Thrombocytosis

• Bernard-Soulier syndrome

What is the main defect in Glanzmann thrombasthenia?

• Fibrinogen

• GP IIb/IIIa receptor

• Von Willebrand Factor

• GPIb/IX/V receptor

What is the clinical manifestation of purpura?

• Small pinpoint spots

• Larger areas of bleeding

• Normal skin appearance

• Bruise-like appearance

Which syndrome is associated with a deficiency of ADAMTS 13?

• Thrombotic Thrombocytopenic Purpura

• Hemolytic Uremic Syndrome

• Aplastic Anemia

• Wiskott-Aldrich Syndrome

What is the typical platelet count in thrombocytosis?

• Normal

• >400 x 10^9/L

• 150-400 x 10^9/L

• <150 x 10^9/L

Which of the following is a sign of increased platelet sequestration?

• Purpura

• Thrombocytopenia

• Splenomegaly

• Petechiae

What is the primary defect in Bernard-Soulier syndrome?

• GPIb/IX/V receptor

• GP IIb/IIIa receptor

• Von Willebrand Factor

• Fibrinogen