Pharma Models Quiz

Factors affecting simple diffusion include the following except :

• Gradient (Concentration of drugs & Electric of ions)

• Molecular weight & size.

• the presence of a protein carrier

For weak base and acid drugs:

• The unionized (non-polar) form is lipid soluble and easily absorbed.

• The unionized (non-polar) form is water soluble and easily absorbed.

• Ionized (polar) form of drugs is lipid soluble and easily absorbed

Filtration of drugs is characterized by the following except :

• Along hydrostatic and osmotic gradients

• No carrier or energy needed

• Molecular weight in more than 500

Filtration of drugs is characterized by the following except :

• Along hydrostatic and osmotic gradients

• a protein carrier is needed

• Molecular weight in less than 500

Facilitated Diffusion is characterized by the following except :

• Along concentration gradient

• Needs a protien carrier → Site for Saturation & Competition .

• Energy is needed.

Active Transport is characterized by the following except :

• Against concentration gradient

• Needs a protien carrier

• No energy or enzymes are needed

Absorption of Vit B12 + Intrinsic factor occurs by:

• Pinocytosis (Cell Drinking)

• Facilitated Diffusion

• Filtration

Absorption of Glucose occurs by:

• Pinocytosis (Cell Drinking)

• Facilitated Diffusion

• Active Transport

Factors affecting absorption include the following except :

• solubility, ionization , and valency of Drugs.

• route of administration, surface area and vascularity.

• number of plasma proteins

Disadvantages of Oral route include the following except :.

• rapid onset.

• produce G.I.T. upsets.

• first pass effect.