Viral Infection Meds

Which antiviral medication is most commonly used for the prevention and treatment of influenza and requires renal dose adjustment?

• Oseltamivir

• Zanamivir

• Baloxavir marboxil

• Amantadine

Which influenza medication is only available as an inhaled dosage form and should be avoided in patients with COPD or asthma?

• Zanamivir

• Peramivir

• Rimantadine

• Baloxavir marboxil

A patient hospitalized with influenza infection and who is immunocompromised should avoid which of the following medications?

• Baloxavir marboxil

• Oseltamivir

• Peramivir

• Zanamivir

Why are Amantadine and Rimantadine currently not recommended for the treatment or chemoprophylaxis of influenza?

• Widespread resistance to circulating strains of influenza A virus

• Severe adverse effects

• High cost

• Only available as intravenous injection

A physician is treating a patient who cannot take oral medications for influenza. Which medication is most appropriate for this patient?

• Peramivir

• Oseltamivir

• Baloxavir marboxil

• Amantadine

Which of the following COVID-19 pharmacotherapies requires renal dose adjustment?

• Dexamethasone

• Remdesivir

• Nirmatrelvir/ritonavir

• Molnupiravir

What is a notable adverse effect associated with dexamethasone therapy in COVID-19 patients?

• Mutagenesis

• Hyperglycemia

• VTE (Venous Thromboembolism)

• GI perforation

Which medication is only available as an intravenous dosage form for COVID-19 treatment?

• Molnupiravir

• Remdesivir

• Baricitinib

• Nirmatrelvir/ritonavir

A patient with symptomatic COVID-19 and risk factors for disease progression, who cannot use nirmatrelvir/ritonavir, is being considered for oral therapy. Which medication is recommended by NIH guidelines in this scenario?

• Remdesivir

• Dexamethasone

• Molnupiravir

• Tocilizumab

A hospitalized COVID-19 patient is receiving dexamethasone and has rapidly increasing oxygen needs and systemic inflammation. What is the rationale for adding tocilizumab or baricitinib to their therapy, and what are the key considerations for their use?

• To reduce mutagenesis; avoid in pregnancy

• To manage hyperglycemia; only use in outpatients

• To address systemic inflammation; monitor for infection and GI perforation

• To prevent renal dysfunction; use only in patients under 18