POST TEST VIBRIO

Which gene combination is detected in PCR-based diagnostics to confirm the presence of toxigenic Vibrio cholerae?

• ctxB, ompF, tcpI

• tcpA, ctxA, ompW

• zot, ace, ctxC

• ompA, ctxD, tcpX

• LPS, zot, ace

What is the most appropriate immediate treatment for a child presenting with severe dehydration due to cholera?

• Oral rehydration salts (ORS) only

• Zinc supplementation only

• Ciprofloxacin 500 mg orally

• Intravenous fluid resuscitation

• Antipyretics and probiotics
  

. Which of the following Vibrio species is most commonly associated with wound infections following seawater exposure?

• Vibrio cholerae

• Vibrio mimicus

• Vibrio alginolyticus

• Vibrio vulnificus

• Vibrio parahaemolyticus

What is the function of the cholera toxin’s B subunit?

• Enzymatically activates Gsα

• Binds to GM1 ganglioside receptors on enterocytes

• Causes rice-water stools directly

• Inhibits water absorption in colon

• . Degrades intestinal mucus barrier

What is the key mechanism by which Vibrio cholerae causes profuse watery diarrhea?

• Direct cytolysis of epithelial cells

• Inflammatory cytokine storm in the intestine

• Overactivation of adenylate cyclase via cholera toxin

• Blockade of sodium-glucose transporters

• Disruption of epithelial junctions by LPS