Human Skin and Wound Healing

What happens during the proliferative stage of wound healing?

• Collagen deposition occurs and new tissue is formed to replace damaged tissue.

• Inflammation decreases and blood flow is reduced.

• Scabs form to protect the wound from infection.

• The wound becomes completely healed without any tissue formation.

What is the role of keratinocytes in wound healing?

• Keratinocytes are responsible for re-epithelialization, covering the wound with new skin.

• Keratinocytes produce collagen to strengthen the wound area.

• Keratinocytes help in the formation of blood clots at the wound site.

• Keratinocytes secrete enzymes that break down dead tissue.

What is the fibrous protein produced by fibroblast cells during wound healing?

• Keratin

• Elastin

• Collagen

• Actin

What type of cells produce collagen fibers?

• Chondrocytes

• Osteoblasts

• Fibroblast cells

• Adipocytes

How do fibroblasts contribute to wound healing?

• By producing collagen and other extracellular matrix components that support tissue repair.

• By promoting inflammation and preventing infection.

• By forming a protective barrier against pathogens.

• By generating new blood vessels to supply nutrients.

What role do white blood cells play in wound healing?

• They help to fight infection and clear debris from the wound site, facilitating the healing process.

• They produce collagen to strengthen the wound area.

• They form a protective barrier over the wound to prevent further injury.

• They release enzymes that speed up the clotting process.

What factors can impair wound healing?

• Poor nutrition, infection, chronic diseases (like diabetes), and certain medications

• Excessive exercise, high protein diet, and hydration

• Regular sleep patterns, balanced diet, and stress management

• Frequent hand washing, avoiding sunlight, and using moisturizers

What is hemostasis in the context of wound healing?

• Hemostasis is the process of stopping bleeding immediately after an injury, involving blood clot formation.

• Hemostasis is the process of promoting inflammation to heal wounds.

• Hemostasis is the process of tissue regeneration after a wound.

• Hemostasis is the process of cleaning the wound to prevent infection.

What is the significance of growth factors in wound healing?

• They are hormones that regulate blood pressure.

• They are signaling molecules that promote cell proliferation, migration, and differentiation, essential for effective wound healing.

• They are proteins that only help in the formation of scars.

• They are enzymes that break down dead tissue.

What is the extracellular matrix and its role in wound healing?

• A network of proteins and carbohydrates that provides structural support to cells and is crucial for tissue repair.

• A type of cell that helps in the formation of blood clots.

• A fluid that fills the spaces between cells in tissues.

• A collection of immune cells that fight infections during healing.