When T cells leave the bone marrow and enter the thymus, they are

BIO-358 Topic 5 Quiz

Quiz
•
Biology
•
University
•
Hard

Karen Denzler
FREE Resource
15 questions
Show all answers
1.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
double negative
double positive
single positive, either CD4+ or CD8+
mature naive T cells
2.
FILL IN THE BLANK QUESTION
1 min • 1 pt
Double positive T cells are found in what region of the thymus
3.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Where does positive selection of T cell occur?
bone marrow
Cortex of the thymus
Medulla of the thymus
Subcapsular region of the thymus
4.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
The purpose of negative selection is to
delete all T cells that are still double positive
delete T cells that interact with MHC molecules
delete T cells that recognize self antigens
prepare T cells for positive selection
5.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
The transcription factors, ThPOK and Runx3, promote development of
CD8+ and CD4+ T cells
B cell precursors
T reg cells
CD4+ and CD8+ T cells
6.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
The transcription factor that promotes expression of many self proteins in the thymus and is used in negative selection is
Terminal deoxynucleotidyl transferase (TdT)
AutoImmune REgulator (AIRE)
ThPOK
Runx3
7.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
The organ that filters antigens present in the blood is the
heart
lymph node
spleen
bone marrow
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