BIO-358 Topic 5 Quiz

BIO-358 Topic 5 Quiz

University

15 Qs

quiz-placeholder

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BIO-358 Topic 5 Quiz

BIO-358 Topic 5 Quiz

Assessment

Quiz

Biology

University

Hard

Created by

Karen Denzler

FREE Resource

15 questions

Show all answers

1.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

When T cells leave the bone marrow and enter the thymus, they are

double negative

double positive

single positive, either CD4+ or CD8+

mature naive T cells

2.

FILL IN THE BLANK QUESTION

1 min • 1 pt

Double positive T cells are found in what region of the thymus

3.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Where does positive selection of T cell occur?

bone marrow

Cortex of the thymus

Medulla of the thymus

Subcapsular region of the thymus

4.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

The purpose of negative selection is to

delete all T cells that are still double positive

delete T cells that interact with MHC molecules

delete T cells that recognize self antigens

prepare T cells for positive selection

5.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

The transcription factors, ThPOK and Runx3, promote development of

CD8+ and CD4+ T cells

B cell precursors

T reg cells

CD4+ and CD8+ T cells

6.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

The transcription factor that promotes expression of many self proteins in the thymus and is used in negative selection is

Terminal deoxynucleotidyl transferase (TdT)

AutoImmune REgulator (AIRE)

ThPOK

Runx3

7.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

The organ that filters antigens present in the blood is the

heart

lymph node

spleen

bone marrow

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