Genomics - L2

Do viruses exhibit metabolic activity on their own?

• Yes, they generate ATP independently
• No, they rely entirely on host cells
• Only when infecting bacteria
• Yes, but only during replication

Which DNA form is most common under physiological (cellular) conditions?

• A form
• B form
• Z form
• C form

Which DNA form is left-handed and has a zigzag-shaped backbone?

• A form
• B form
• Z form
• R form

Compared to B-DNA, how is A-DNA structurally different?

• It is more extended and relaxed
• It is more compact with tilted base pairs
• It is denatured and single-stranded
• It is looser with wider major grooves

In high humidity, DNA typically exists in which form?

• A form
• B form
• Z form
• C form

Under low humidity conditions (around 75%), DNA usually takes on which form?

• A form
• B form
• Z form
• D form

In the A form of DNA, how are the planes of the base pairs oriented relative to the helical axis?

• Parallel to the axis
• Perpendicular to the axis
• Tilted and not perpendicular to the axis
• Randomly oriented

When DNA hybridizes with RNA in solution, the DNA takes on which structural form?

• B form
• Z form
• A form
• D form

When DNA is wound into a left-handed double helix, it is referred to as what?

• A-DNA
• B-DNA
• Z-DNA
• D-DNA

What is a structural difference between Z-DNA and B-DNA?

• Z-DNA has evenly spaced grooves; B-DNA has irregular ones
• B-DNA has distinct major and minor grooves; Z-DNA shows minimal groove width difference
• Z-DNA has no grooves; B-DNA has only one groove
• B-DNA has a flat backbone; Z-DNA has bulges