Lesson 14.4: Mutations

A mutation is

• a change in the DNA sequence.

• a change in the tRNA sequence.

• heritable.

• non-heritable.

A point mutation is a change in a single what?

• Nucleotide

• Chromosome

• Gene

• Protein

A chromosomal mutation is a change in what?

• Nucleotides

• Chromosomes

• Genes

• Proteins

Match the following.

• One base is changed to a different base

• Point

• Chromosomes are changed

• Substitution

• Bases are inserted or deleted

• Frameshift

• A single base pair is changed

• Chromosomal

Organize these options into the right categories

Groups:

(a) Point

,

(b) Chromosomal

• Frameshift

• Duplication

• Translocation

• Substitution

• Inversion

• Deletion

Match the following.

• Doesn't affect the amino acid sequence

• Silent mutation

• Results in a new amino acid

• Mutagen

• Results in a stop codon

• Missense mutation

• Tobacco smoke, X rays

• Nonsense mutation

What is a mutagen?

• A type of organism

• A chemical or physical agent that causes mutations

• A type of cell

• A genetic disorder

A frameshift mutation is:

• a change in a single nucleotide base pair.

• an insertion or deletion of nucleotides that changes the reading frame of the genetic message.

• a substitution of one nucleotide for another.

• a mutation that does not affect the protein sequence.

Match the following chromosomal mutations.

• Extra copy of all or part is made

• Deletion

• Parts break off and attach to another

• Inversion

• Reverses the direction of parts

• Duplication

• all or part is lost

• Translocation